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nerelimomab (CAT#: TAB-768)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Anti-TNF alpha Recombinant Antibody TAB-768 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant mouse monoclonal antibody expressed in CHO binding to human TNF alpha. Nerelimomab is a mouse monoclonal antibody acting as a TNF inhibitor.
  • Target
  • TNF alpha
  • Type
  • IgG1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • CAS
  • 162774-06-3
  • Molecular Weight
  • Approximately 150 kDa
  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Size
  • 1mg
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Introduction
  • Nerelimomab is a mouse monoclonal antibody acting as a TNF inhibitor.
  • Antigen Description
  • This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
  • Function
  • cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding;
  • Synonyms
  • TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNF-alpha;

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